TargetScape ™ provides deep immune profiling of antigen-specific CD8 T cells utilizing a novel combinatorial barcoding MHC-tetramer strategy.
This highly sensitive method enables the probing of hundreds of candidate T cell antigen targets in a single sample of unstimulated blood or dissociated tissue, leading to the identification of rare antigen-specific T cells for longitudinal disease immunomonitoring or the evaluation of treatment-associated changes.
UltraScape™ is a cutting-edge immune profiling assay designed to characterize and monitor key immune cell populations over time, using 120 markers in one sample.
With our method, you can simultaneously characterize several immune cell subpopulations, such as T cells, B cells, NK cells, Basophils, HSCs and myeloid cells, to investigate activation, proliferation, differentiation, trafficking, apoptosis, and inhibitory molecule expression. For additional insight generation, the UltraScape™assay may be combined with ImmunoScape’s signature TargetScape™ assay, to screen and identify large numbers of CD8 T cell antigen specificities.
Use ImmunoScape’s powerful, secure, integrated cloud-based bioinformatics platform to address and shed light on your key biological questions.
Cytographer® enables the processing, analysing and visualizing of high-dimensional single cell data, including the screening and identification of antigen-specific T cells, to generate meaningful biological insights and correlations with clinical parameters. Cytographer® can support CyTOF, flow cytometry and RNAseq datasets, and incorporates methodologies and tools for high-throughput processing, high-dimensional data reduction, immune subset detection, statistics and correlations analysis, as well as state of the art algorithms for biomarker discovery.