About Us
ImmunoScape discovers and develops a diverse and risk-balanced portfolio of novel TCRs against solid tumors. Using a multi-facetted approach together with deep technology know-how we develop highly effective and differentiated TCR-based therapies for solid tumors:
Right TCR – Our validated Deep Immunomics and Machine Learning platforms enable at scale selection of specific, safe and novel TCR-based therapies
High Value Targets – We use a diverse set of shared antigens including many novel and ImmunoScape exclusive antigens to broaden tumor targetability
More Patients – Our robust HLA library covers >85% of the population from North America, Europe and South East Asia
We are building a robust TCR-based therapeutics pipeline with multiple discovery programs ongoing to address the high unmet need for solid tumor treatment.
Founding year
Employees
Peer-reviewed Articles
Offices + Labs
Executive Team
Choon-Peng Ng, MBA
CHIEF EXECUTIVE OFFICER
Dan MacLeod, PhD
VICE PRESIDENT, DISCOVERY
Romi Chandiramani, CA
CHIEF FINANCIAL OFFICER
Mathew Cobbett, MBA
VICE PRESIDENT, NORTH AMERICA
Michael Fehlings, PhD
VICE PRESIDENT, INNOVATION
Tania Catarino Ribeiro, PhD
SENIOR DIRECTOR, CMC
Board of Directors
Choon-Peng Ng, MBA
CHIEF EXECUTIVE OFFICER
Alessandra Nardin, DVM
VICE PRESIDENT STRATEGY
Naonori Kurokawa
DIRECTOR, UTEC
David Michael
MANAGING PARTNER, ANZU PARTNERS
Adrian Woolfson, PhD
COFOUNDER, PRESIDENT, AND EXECUTIVE CHAIRMAN OF REPLAY
Scientific Advisory Board
Evan Newell, PhD
CO-FOUNDER/ADVISOR, IMMUNOSCAPE; ASSOCIATE PROFESSOR, FRED HUTCHINSON CANCER RESEARCH CENTER
Philip Greenberg, MD
PROFESSOR, UNIVERSITY OF WASHINGTON; HEAD OF PROGRAM (IMMUNOLOGY), FRED HUTCHINSON CANCER RESEARCH CENTER
Paul Thomas, PhD
MEMBER, ST. JUDE CHILDREN'S RESEARCH HOSPITAL IN MEMPHIS, TN
Patrick Reeves, PhD
TEAM LEADER, MASSACHUSETTS GENERAL HOSPITAL
Rachel Humphrey, MD
CHIEF EXECUTIVE OFFICER, NORMUNITY
Adrian Woolfson, PhD
COFOUNDER, PRESIDENT, AND EXECUTIVE CHAIRMAN OF REPLAY
John Tsang, PhD
PROFESSOR OF IMMUNOBIOLOGY AND BIOMEDICAL ENGINEERING, YALE UNIVERSITY
Our Investors
Choon-Peng Ng, MBA
CHIEF EXECUTIVE OFFICER
Choon holds an MBA from the University of Michigan’s Ross Business School and completed Executive Education at IMD in Lausanne, Switzerland. He graduated with a BSc (Economics) from the London School of Economics under a scholarship from the Singapore Armed Forces.
Alessandra Nardin, DVM
VICE PRESIDENT, STRATEGY
Alessandra co-founded ImmunoScape and serves as VP Strategy and Board Director. With a clinical background in Veterinary Medicine from the University of Parma, she has 25 years of international experience in the immunotherapy and immunomonitoring fields, having worked in both academic and industry environments across Italy, US, France and Singapore.
Alessandra started as a Research Fellow at the Istituto Zooprofilattico della Lombardia e dell’Emilia, where she focused on diagnostic and immunomonitoring techniques for viral diseases. In the late 90’s, as a Research Associate at the University of Virginia, she worked on the development of bispecific antibody constructs for the clearance of blood-borne pathogens and tumors.
Alessandra joined IDM Pharma in 1999, and as a Manager of Research Programs led investigations in cancer immunotherapy strategies and preclinical studies on dendritic cell and macrophage-based drug candidates targeting melanoma, bladder cancer and osteosarcoma. In 2006, she joined Singapore Immunology Network, A*STAR, where she rose to Head, Translational Immunology, and expanded into business development and IP valorization while supporting clinical studies in antibody immunotherapy and vaccines. She has published 25 peer-reviewed scientific papers in the field of immunology.
Romi Chandiramani, CA
CHIEF FINANCIAL OFFICER
As CFO, Romi is a part of the ImmunoScape Management team, and is responsible for Finance, Administration, Investor Relations, HR, and Procurement. Romi is a finance & management professional with extensive international experience.
Previously, Romi was Global CFO for Vela Diagnostics, where he was instrumental in raising PE & direct investor finance, driving M&A activity and building up of organization structures, systems & processes to sustainable operations. Prior to this, Romi worked across the world in various regional, country and business divisional CFO roles as a business partner in the German MNC Siemens. At Siemens, Romi contributed extensively in roles managing Finance, Accounting, Taxation, Audit, Costing, Controlling, Strategic Planning & management, M&A activities, Business Partnering, Project Pricing, Commercial Negotiating & Contracting, Project Controlling & Management.
Romi holds an honours degree in Commerce from Delhi University and he is member of the Institute of Chartered Accountants.
Mathew Cobbett, MBA
VICE PRESIDENT, NORTH AMERICA
Michael Fehlings, PhD
VICE PRESIDENT, OPERATIONS AND DEVELOPMENT
Michael co-founded ImmunoScape and serves as Vice President, Innovation. During his PhD Michael has focused on profiling human primary antigen-presenting cells in pathogenic interactions. As a postdoctoral fellow in Evan Newell’s laboratory at the Singapore Immunology Network, A*STAR, he gained in-depth experience in identifying and characterizing antigen-specific T cells in the fields of infectious diseases and cancer by using multiplexing tetramer and high-dimensional immune profiling technologies.
Michael has published in several peer-reviewed scientific papers in the field of immunology, including Nature, Cell, Immunity, Nature Communications and others.
Tania Catarino Ribeiro, PhD
SENIOR DIRECTOR, CMC
Tania holds a Ph.D. in Molecular Biology from UNL (Lisbon, Portugal) in collaboration with Harvard Medical School and Caen University (France). Her academic journey also includes a MSc in Clinical Microbiology in collaboration with Lausanne University (Switzerland) and a BSc in Biochemistry. Additionally, Tania has acquired professional certifications in Project Management and Clinical Trials Monitoring.
Dan MacLeod, PhD
VICE PRESIDENT, DISCOVERY
Dan received a B.A. from Northwestern University with a double major in biochemistry and psychology, and a Ph.D. in molecular pathology and biomedical sciences from the University of California, San Diego.
Naonori Kurokawa
DIRECTOR, UTEC
Prior to UTEC, Nori joined ARCH Venture Partners as an intern in February 2008. He received his MBA from the University of Chicago Booth School of Business where he won the first place and the award for the most innovative plan in Edward L. Kaplan New Venture Challenge 2008. He earned his Ph.D. in applied physics from Osaka University in 2003.
Mathew Cobbett, MBA
VICE PRESIDENT, NORTH AMERICA
Prior to his work at Anzu, Mr. Michael spent 24 years at The Boston Consulting Group, where he was a Senior Partner and served in numerous leadership roles, working in the firm’s offices in Silicon Valley, Hong Kong, and Beijing. Mr. Michael has a B.A. in economics from Harvard and an MBA from Stanford.
Adrian Woolfson, PhD
COFOUNDER, PRESIDENT, AND EXECUTIVE CHAIRMAN OF REPLAY
Evan Newell, PhD
CO-FOUNDER/ADVISOR, IMMUNOSCAPE; ASSOCIATE PROFESSOR, FRED HUTCHINSON CANCER RESEARCH CENTER
Evan began his pMHC-tetramer work at Stanford as a postdoctoral fellow in Mark Davis’ laboratory, and continued to advance the methodology to identify novel correlates of clinical outcomes for a variety of diseases as a Principal Investigator at Singapore Immunology Network, A*STAR, prior to joining Fred Hutch in Seattle. He has published over 100 peer-reviewed scientific papers in the field of immunology.
Philip Greenberg, MD
PROFESSOR, UNIVERSITY OF WASHINGTON; HEAD OF PROGRAM (IMMUNOLOGY), FRED HUTCHINSON CANCER RESEARCH CENTER
He has authored more than 280 manuscripts and received many honors including Cancer Research Institute’s William B. Coley Award for Distinguished Research in Tumor Immunology, Society for Immunotherapy of Cancer Richard Smalley Memorial Career Award, American Society of Hematology E. Donnall Thomas Prize for Pioneering Research Achievements in Hematology, and the Precision Medicine World Conference Luminary Award; and he has been elected to numerous honorary societies. He was an elected member of the Board of Directors for the AACR, currently serves on advisory boards for several major cancer centers, and also serves on numerous editorial boards, including Cancer Cell and Cancer Immunology and Immunotherapy, and as an Editor-in-Chief for the AACR journal, Cancer Immunology Research.
Paul Thomas, PhD
MEMBER, ST. JUDE CHILDREN'S RESEARCH HOSPITAL IN MEMPHIS, TN
Dr. Thomas obtained his undergraduate degree in Biology and Philosophy at Wake Forest University. He did his PhD training at Harvard University, working on the innate immune response to Schistosoma-associated carbohydrates and their role in promoting Th2 responses. From there, he moved to St. Jude Children’s Research Hospital for a postdoctoral fellowship with Peter Doherty on T cell responses in the influenza model. In 2009, he started his own lab St. Jude, from which he has published over 150 peer-reviewed papers on TCR biology, immunological mechanisms of disease severity in human viral infections, and cellular immunology.
Patrick Reeves, PhD
TEAM LEADER, MASSACHUSETTS GENERAL HOSPITAL
John Tsang, PhD
PROFESSOR OF IMMUNOBIOLOGY AND BIOMEDICAL ENGINEERING, YALE UNIVERSITY
Rachel Humphrey, MD
CHIEF EXECUTIVE OFFICER, NEW VENTURE